Cletus Strain runs the Blighters in Lambeth for Crawford Starrick and is the leader you fight in Gang War: Lambeth in Assassin's Creed Syndicate. He has a taste for theatrics and likes to smother enemies in smoke.
Strain is killed by one of the twins during the Lambeth gang war, and the Rooks take the borough.
Strain's borough is weakened target by target before the war. The Templars to remove are Martin Church, the Lambeth Bullies (Ada and Clyde Cobleigh) and the Fletchers (Josephine and Francis); the Blighter strongholds are Battersea Bellows and Echostreet Alley; the bounties are Leopold Bacchus, Mildred Graves and Jesse Butler; and the children to free work in the Strain & Boil factory. Lambeth is also where you find Lambeth Asylum and Alexander Graham Bell's workshop.
He hangs back while his gang trades blows with the Rooks and steps in only after the Blighters have lost a lot of men. The game paints him as a showman who likes to choke his opponents with smoke, and he goes into the war holding a smoke grenade.
Bloody Nora
Bloody Nora is the Blighter leader of the City of London in Assassin's Creed Syndicate and the boss you face in Gang War: City of London. Her nickname comes from the ruthless violence that won her a place in the gang.
Crawford Starrick
Crawford Starrick is the main antagonist of Assassin's Creed Syndicate: Grand Master of the British Templars and the industrialist who controls London in 1868 through his factories, railways, banks, the Blighters gang and a ring of Templar lieutenants. Every major target the Frye twins kill is one of his people, and the main story builds toward a final confrontation with him at Buckingham Palace.
David Brewster
Sir David Brewster is the Scottish scientist and Templar experimenting on an Apple of Eden in a hidden laboratory under a Croydon train yard. He is Evie Frye's first target in Assassin's Creed Syndicate, in the memory A Simple Plan, whose optional objectives include air assassinating him.
Earl of Cardigan
The Earl of Cardigan, James Brudenell, is the Templar politician behind the plot to kill Prime Minister Benjamin Disraeli in Sequence 7 of Assassin's Creed Syndicate. Known in Templar letters only as B, he is the target of the memory Motion to Impeach at the Palace of Westminster.