76 characters in Ghost of Tsushima.
| Name | Role | Affiliation | Status |
|---|---|---|---|
| Hirotsune | Minor | Straw Hats | |
| Hochi | Minor | Cedar Temple | |
| Ichi | Supporting | — | |
| Ikeda | Minor | Clan Kikuchi | |
 Jin Sakai | Protagonist | Clan Sakai | |
| Jinroku | Minor | — | |
| Junshin | Supporting | Golden Temple | |
| Kaede | Minor | Clan Nagao | |
| Kajiwara | Minor | Clan Adachi (formerly) | |
| Kanetomo | Minor | Straw Hats | |
 Kazumasa Sakai | Supporting | Clan Sakai | |
| Kenji | Companion | The Ghost | |
| Kharchu | Antagonist | Mongol Empire | |
 Khotun Khan | Antagonist | Mongol Empire | |
| Khunbish | Antagonist | Eagle Tribe | |
| Kiyochika | Minor | Straw Hats | |
| Kojiro | Antagonist | Straw Hats | |
| Lady Sanjo | Minor | — | |
 Lord Shimura | Supporting | Clan Shimura | |
| Mai | Minor | — | |
| Mamushi brothers | Antagonist | Slavers | |
| Masako Adachi | Companion | Clan Adachi | |
| Norio | Companion | Cedar Temple | |
| Omura | Minor | — |