Image: UbisoftOfficial screenshot from Ubisoft.
Friendly Skies unlocks when you destroy 16 Anti-Aircraft Cannons in solo play. AA sites also pay out Depleted Uranium and open the sky for your aircraft, so they are worth hitting anyway.
1. Find an Anti-Aircraft Site on the map. 2. Reach it by road or on foot, not by air. 3. Destroy the cannon with explosives. 4. Repeat until you hit 16.
A rocket launcher or C4 makes each site quick. Valle De Oro has nine sites, the most of any region, so it is a good place to rack them up. Clearing AA early makes the rest of the map faster to cross.