Black Hole Shield is a gear perk that greatly raises your overall damage resistance and cuts fall damage. It is one of the strongest pure defense perks in the game.
You take less damage from every source, and long drops hurt less too. It makes you much harder to kill in open fights.
Wear one of the gear pieces that carry it: Polydimensional Sheath. Each piece only takes one body slot, so plan around the other perks you want.
Yes. A broad damage reduction is useful in every situation, especially on higher difficulty.