7 regions
Belknap is the volcanic region south of the Cascade, home to Ada Tucker's Hot Springs camp and the town of Marion Forks. You come here early for Tucker's work and stay for its seven Hordes and three infestations.
Cascade is the northern starting region, in the Farewell wilderness around Copeland's Camp at Peaceful Lake. It is where you learn the game, and it still has 8 Hordes and 4 NERO research sites to come back for.
Crater Lake is the far southern region built around the real lake and Wizard Island, the Militia's headquarters. It opens in the second half of the story and has the most encampment jobs and NERO research sites in the game.
Highway 97 is the southern stretch of US highway running through Chemult and past Chemult Community College. It has more Hordes than any other region, including the 300-strong Lobert Draw Ridge Horde, so bring your best gear.
Iron Butte is the Rippers' home territory in the east, locked until late in the story. Come here for its 11 R.I.P. Sermons, two Ripper ambush camps, the Rogue Tunnel checkpoint and the Cloverdale research facility.
Lost Lake is the central region of the map, built around a resort lake that holds Iron Mike's Camp. It becomes your main base for the middle of the story and packs 6 Hordes, 3 infestations and Sherman's Camp.
Pinnacles is a cut region east of Highway 97. You cannot enter it; both ways in are blocked. Data miners found plans for a sixth camp, Fort Klamath, ranches and farms there, plus a cut Act 4 mission.
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Red Cross Plane Crash
A wrecked Red Cross supply plane on the Ripper side of the Lost Lake border. In Playing All Night, Deacon sneaks into Ripper land to find antibiotics for Boozer here and has to kill a Breaker to get them.
Sherman's Camp
Sherman's Camp is an abandoned historic town in Lost Lake where a survivor settlement was wiped out early in the outbreak. Now it holds an infestation and a Horde, and you visit it with Iron Mike in the story.
Sugarpine Butte
Sugarpine Butte is an Iron Butte spot where a historical marker tells the story of a giant iron meteorite found nearby. It is a collectible stop, worth a detour if you are hunting markers.
Teller Cabin
Teller Cabin is a pioneer homestead in the Cascade wilderness with a historical marker about the Teller family. It is a collectible stop with one of the darker stories in the marker set.
The Burger Mart
The Burger Mart is a burger joint in Chemult on Highway 97. It has no mission of its own. Chemult is still worth a scavenging run if you keep clear of the Horde at the train station.
The Chateau
The Chateau is a restaurant in Chemult on Highway 97. It has no mission of its own. Chemult is still worth a scavenging run if you keep clear of the Horde at the train station.
The Horseshoe Cafe
The Horseshoe Cafe is a diner-style cafe in Chemult on Highway 97. It has no mission of its own. Chemult is still worth a scavenging run if you keep clear of the Horde at the train station.
Thielsen Pass Cabin
An unmarked hut near Thielsen Pass where Deacon and Sarah sat out a blizzard before the outbreak. It has no map marker and matters only for the memory it holds.
Timber Auto Parts
Timber Auto Parts is an auto parts shop in Chemult on Highway 97. It has no mission of its own. Chemult is still worth a scavenging run if you keep clear of the Horde at the train station.