4 storylines
The Lunar Games is a quest chain built around games held in Vale Sangora. It is your route to the boyar Bakir: max out his anger and his servant Farkas invites you into a deadly tournament.
A Pilgrimage for Power is a set of side quests where Coen tracks down Uriash glyphs on stone monuments and learns their shaman magic. Each part ends with a new spell manual, so they are a good way to grow your sorcery.
The prologue is the opening part of the story. It is set in Laslea, before the open world unlocks. Every side quest here is missable, so do them before the Blood Mass.
The Blood of Dawnwalker is the main quest. Its goal is to rescue Coen's family within 30 days and 30 nights. Every other quest you take spends some of that time, so it shapes how you plan the whole game.